Delayed Bone Age Might Accelerate the Response to Human Growth Hormone Treatment in Small for Gestational Age Children with Short Stature
Table 2
Initial clinical and laboratory characteristics when patients were classified according to the presence of growth hormone deficiency (GHD).
M : F
Without GHD group (N = 13)
With GHD group (N = 14)
value
3 : 10
7 : 7
Gestational age (months)
38.5 ± 2.26
37.0 ± 2.96
0.154
Birth weight (g)
2237.69 ± 500.76
2240.71 ± 410.14
0.986
Age (years)
7.05 ± 1.85
7.26 ± 1.94
0.784
BMI (kg/m2, z-score)
−0.46 ± 0.85
−0.55 ± 1.01
0.805
Height SDS
−2.63 ± 0.25
−2.42 ± 0.33
0.239
BA (years)
5.3 ± 2.7
4.6 ± 2.8
0.534
CA-BA (years)
1.71 ± 1.28
2.61 ± 1.59
0.117
BA/CA
0.72 ± 0.23
0.60 ± 0.24
0.200
IGF-1 SDS
−1.03 ± 0.9
−1.07 ± 0.86
0.921
rhGH (IU/kg/day)
0.16 ± 0.03
0.15 ± 0.04
0.341
N, number; M : F, male: female (number); BA, bone age; CA-BA, differences between bone age and chronological age; BA/CA, bone age to chronological age ratio; rhGH, recombinant human growth hormone; GHD, growth hormone deficiency.
