Research Article

Gender-Specific Differences on the Association of Hypertension with Subclinical Thyroid Dysfunction

Table 4

Increased SBP and DBP in different genders according to thyroid functions.

Males SBPMales DBPFemales SBPFemales DBP

Thyroid functions#Crude OR (CI)Adjusted OR (CI)#Crude OR (CI)Adjusted OR (CI)#Crude OR (CI)Adjusted OR (CI)#Crude OR (CI)Adjusted OR (CI)#
Subclinical hyperthyroidism TSH ≤ 0.3 μlU/mL0.948 (0.346–2.601)1.285 (0.432–3.828)0.588 (0.247–1.403)0.796 (0.317–1.998)1.648 (0.816–3.329)1.258 (0.537–2.948)1.453 (0.781–2.703)1.284 (0.653–2.524)
0.3 μlU/mL < TSH ≤ 1.0 μlU/mL0.906 (0.750–1.095)0.969 (0.789–1.189)0.823 (0.694–0.975)0.847 (0.707–1.014)1.315 (0.972–1.779)1.323 (0.903–1.938)0.755 (0.580–0.982)0.733 (0.547–1.001)
1.0 μlU/mL < TSH ≤ 2.0 μlU/mL0.845 (0.747–1.001)0.894 (0.782–1.022)0.892 (0.797–1.001)0.919 (0.816–1.036)1.012 (0.844–1.213)1.138 (0.912–1.420)1.002 (0.868–1.156)1.085 (0.926–1.271)
2.0 μlU/mL < TSH ≤ 3.0 μlU/mLReferenceReferenceReferenceReferenceReferenceReferenceReferenceReference
3.0 μlU/mL < TSH ≤ 4.0 μlU/mL0.887 (0.730–1.078)0.788 (0.637–1.001)0.847 (0.711–1.009)0.788 (0.654–1.001)1.291 (1.041–1.600)1.333 (1.028–1.729)1.153 (0.966–1.376)1.107 (0.911–1.345)
4.0 μlU/mL < TSH ≤ 5.0 μlU/mL1.125 (0.850–1.489)1.072 (0.788–1.460)0.952 (0.729–1.243)0.978 (0.736–1.301)1.579 (1.226–2.033)1.326 (1.001–1.805)1.270 (1.022–1.577)1. 081 (0.850–1.375)
Subclinical hypothyroidism TSH > 5.0 μlU/mL1.451 (1.085–1.939)1.154 (0.835–1.595)1.479 (1.077–2.031)1.564 (1.117–2.190)1.862 (1.474–2.352)1.371 (1.032–1.823)1.891 (1.540–2.322)1.604 (1.279–2.012)

TSH = thyroid stimulation hormone; SBP = systolic blood pressure; DBP = diastolic blood pressure; OR = odds ratio; CI = confidence interval. #Logistic regression model including age, body mass index, total cholesterol, triglycerides, alanine aminotransferase, aspartate transaminase, total bilirubin, blood urea nitrogen, creatinine, and fasting glucose as covariates. and .