Research Article

miR-129-5p Inhibits Adipogenesis through Autophagy and May Be a Potential Biomarker for Obesity

Table 2

Clinical characteristics of validation study participants by weight category.

VariableNormal weight control (mean ± SD)Obese patients (mean ± SD) value

Demographic data
Sex (male) (n (%))15 (100%)16 (100%)
Age (years)27.22 ± 1.7727.45 ± 1.790.696

Anthropometric measurements
BMI (kg/m2)21.19 ± 1.3532.01 ± 1.910.0001
WC (cm)76.57 ± 7.89105.96 ± 6.170.0001
HC (cm)93.14 ± 5.02110.37 ± 5.260.0001
WHR0.82 ± 0.060.96 ± 0.040.0001
Fat percentage (%)25.07 ± 4.8932.64 ± 4.090.0001

Biochemical characteristics
Glu (mmol/L)5.07 ± 3.155.35 ± 3.650.016
HBA1C (%)5.13 ± 0.205.43 ± 0.430.0001
TC (mmol/L)4.67 ± 0.835.83 ± 1.290.002
TG (mmol/L)0.92 ± 0.382.71 ± 1.970.001
HDL (mmol/L)1.54 ± 0.291.13 ± 0.210.0001
LDL (mmol/L)2.69 ± 0.643.67 ± 1.000.001
Insulin (IU/L)6.42 ± 2.6419.37 ± 8.480.0001

The data are presented as mean ± SD, and the value was calculated using a two-tailed test; significant values are indicated in bold. BMI, body mass index; WC, waist circumference; HP, hip circumference; WHR, the rate of WC to HP; Glu, glucose; HbAlc, glycosylated hemoglobin; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoproteins; LDL, low-density lipoproteins.