Is a Combination of a GnRH Agonist and Recombinant Growth Hormone an Effective Treatment to Increase the Final Adult Height of Girls with Precocious or Early Puberty?

Figure 4

Forest plots showing the primary outcomes for girls with early puberty or CPP. Forest plots showing (a) the primary outcomes for girls with early puberty after sensitivity analysis. The difference between final adult height standard deviation score (SDS) and initial height SDS for the combination therapy versus no therapy; (b) the primary outcomes for girls with central precocious puberty (CPP) after sensitivity analysis. The difference between final adult height SDS and initial height SDS for the combination therapy versus GnRHa therapy; (c) the primary outcomes for adopted girls with idiopathic CPP after sensitivity analysis. The difference between final adult height SDS and initial height SDS for the combination therapy versus GnRHa therapy.

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