Is a Combination of a GnRH Agonist and Recombinant Growth Hormone an Effective Treatment to Increase the Final Adult Height of Girls with Precocious or Early Puberty?

Figure 3

Forest plots showing the results of the meta-analysis. Forest plots showing results for the meta-analysis of (1.1.1) the difference between final adult height standard deviation score (SDS) and initial height SDS for the combined gonadotropin-releasing hormone analogs (GnRHa) and recombinant human growth hormone (rhGH) group and the rhGH alone group in girls with early puberty; (1.1.2) the difference between the final adult height SDS and initial height SDS for the combined GnRHa and rhGH group and the no treatment group in girls with early puberty; (1.1.3) the difference between final adult height SDS and initial height SDS for the combined GnRHa and rhGH group and the GnRHa alone group for girls with idiopathic central precocious puberty (ICPP). CI: confidence interval.