A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women

Table 2

Baseline and posttreatment endocrine and metabolic parameters of groups A and B of PCOS patients.

	⁢Group A ()			⁢Group B ()
	Baseline	MI plus DCI	p value	Baseline	placebo	value
FSH (mIU/mL)	5.86 ± 1.75	4.96 ± 1.74	ns	5.67 ± 1.11	5.47 ± 0.63	ns
LH (mIU/mL)	12.5 ± 8	8.5 ± 4.04		11.27 ± 7.2	11.25 ± 5.35	ns
E (pg/mL)	47.06 ± 18.20	107.42 ± 92.86		50.37 ± 19.45	52 ± 20.2	ns
Fasting insulin (μU/mL)	20.19 ± 8.14	10.74 ± 5.46		18 ± 8	17.8 ± 8.2	ns
Fasting glucose (mg/dL)	85 ± 5.96	86 ± 7.12	ns	86.2 ± 9.1	84.73 ± 8.3	ns
Free testosterone (ng/dL)	0.76 ± 0.20	0.62 ± 0.15		0.85 ± 0.22	0.83 ± 0.2	ns
SHBG (nmol/L)	24.11 ± 10.35	35.85 ± 24.3		20.44 ± 8.77	21.36 ± 7.57	ns
Androstenedione (ng/mL)	4.25 ± 1.48	4.01 ± 1.70	ns	3.48 ± 1.21	3.12 ± 2.23	ns
DHEAS (μg/dL)	327.32 ± 150.89	347.6 ± 170.98	ns	337.95 ± 155.79	315.83 ± 145.59	ns
HOMA	3.38 ± 1.97	1.97 ± 1.48		3.48 ± 2.02	2.8 ± 1.4	ns

E, 17-beta-Estradiol; P, progesterone; 17OHP, 17-OH-progesterone; SHBG, Sex Hormone Binding Globulin; DHEAS, dehydroepiandrosterone sulphate.