Clinical Study

Growth Hormone Therapy Benefits Pituitary Stalk Interruption Syndrome Patients with Short Stature: A Retrospective Study of 75 Han Chinese

Table 1

Initial characteristics of the 75 patients.

GH treated cohort ()Untreated cohort ()

Sex (male/female) 45/621/3
Chronological age before treatment (year)18.24 ± 5.11 18.96 ± 6.58
Bone age (year)12.1 (5.0~17.0)13.0 (9.0~17.0)
Delayed bone age (year)−4.0 (−11.0~−1.0) −4.0 (−6.0~−1.0)
Height (SDS) −2.08 (−6.93~−2.80)−2.25 (−6.18~−50)
Familial history 00
Malformations 4 1
Breech presentation (%) 93.3 83.0
Perinatal events (%)51.153.3
GHD (%) 100100
GHD + ACTH deficiency (%)62.2 56.6
GHD + TSH deficiency (%)68.9 70.0
GHD + LH/FSH deficiency (%) 95.6 86.6

, untreated cohort compared to GH treated cohort.