Low Magnesium Exacerbates Osteoporosis in Chronic Kidney Disease Patients with Diabetes

Table 1

Characteristics of the 56 nondialysis CKD patients with or without diabetes.

Variables	Total ()	Diabetes ()	Nondiabetes ()
Age (y)	69.0 (58.8–75.8)	68.0 (62.0–77.0)	70 (57.0–74.5)	0.928
Gender
Female	24 (42.9)	15 (55.6)	9 (31.0)	0.064
Male	32 (57.1)	12 (44.4)	20 (69.0)
Estimated GFR (mL/min)	16.5 (10.5–28.8)	13.7 (9.4–29.8)	18.4 (12.0–24.8)	0.302
Chronic kidney disease
Stage 3	13 (23.2)	7 (25.9)	6 (20.7)	0.102
Stage 4	18 (55.4)	5 (18.5)	13 (44.8)
Stage 5	25 (44.6)	15 (55.6)	10 (34.5)
Albumin (g/dL)	3.8 ± 0.4	3.7 ± 0.4	3.9 ± 0.4	0.046
Serum Mg (mmoL/L)
1.82 mg/dL low	6 (10.7)	6 (22.2)	—	0.023
1.82–2.31 mg/dL normal	33 (58.9)	13 (48.1)	20 (69.0)
>2.31 mg/dL high	17 (30.4)	8 (29.6)	9 (31.0)
Osteoporosis
With	22 (39.3)	15 (55.6)	7 (24.1)	0.016
Without	34 (60.7)	12 (44.4)	22 (75.9)

(1) eGFR, estimated glomerular filtration rate.
(2) Comparisons of continuous data between two groups were analyzed by Wilcoxon rank-sumtest. Data are median and range (25th pctl–75th pctl). The -test was used for the difference in the means of two groups. Data are means ± SD.
(3) Categorical data were analyzed by the Chi-square test. When cells have expected count less than 5, data were analyzed by Fisher’s Exact test. Data are number (), percent (%).
(4) A value less than 0.05 was considered statistically significant.