Research Article
Reevaluation of Acromegalic Patients in Long-Term Remission according to Newly Proposed Consensus Criteria for Control of Disease
Table 3
Comparison of metabolic and comorbid data between patients with postglucose GH nadir over (group A) and below 0.4 μg/L (group B) at last follow-up.
| | Parameter | Group A | Group B | | | (GH-n ≥ 0.4 mcg/L) | (GH-n < 0.4 mcg/L) |
| | 11 | 29 | — | | BMI (Kg/m2) | 24.4 ± 4.6 | 28.6 ± 4.4 | ns | | Impaired glucose metabolism (y/n) | 4/7 | 13/16 | ns | | IFG, IGT, DM (n) | 1/2/1 | 0/9/4 | | | Fasting glucose (mg/dL) | 85 ± 14 | 97 ± 20 | ns | | Glucose at 120′ (mg/dL) | 138 ± 57 | 128 ± 36 | ns | | HOMA-IR | 2.0 ± 1.7 | 2.1 ± 1.8 | ns | | Blood hypertension (y/n) | 3/8 | 12/17 | ns | | SBP (mmHg) | 115 ± 15 | 122 ± 12 | ns | | DBP (mmHg) | 74 ± 11 | 79 ± 7 | ns | | Cardio- and/or cerebrovascular disease (y/n) | 6/5 | 10/19 | ns | | Valvular heart disease | 4 | 4 | | Acromegalic cardiomyopathy | 1 | 1 | | Arrhythmias and cardiomyopathy | 0 | 5 | | Acute myocardial infarction | 1 | 0 | | Malignancies (y/n) | 3/8 | 2/27 | ns | | Mammary carcinoma | 1 | 0 | | Monoclonal gammopathy | 2 | 0 | | Olfactory meningioma | 0 | 1 | | Skin melanoma | 0 | 1 | | Colorectal disease | 2/9 | 7/22 | ns | | Diverticula | 0 | 3 | | Dolichocolon | 0 | 1 | | Hyperplastic polyps | 0 | 2 | | Adenomatous polyps | 2 | 1° |
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IFG: impaired fasting glucose; IGT: impaired glucose tolerance; DM: diabetes mellitus; NS: not significant.
Low grade adenomatous tubular polyps, °serrated adenoma with low grade dysplasia.
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