Mammary Fat Can Adjust Prolactin Effect on Mammary Epithelial Cells via Leptin and Estrogen

<table><i>Expression of aromatase mRNA in mammary fat explants and mammary primary culture.</i>  Expression of aromatase  mRNA in fat explants (closed bars) and primary mammary cells (open bars) from a lactating cow, with various concentrations of prolactin (0.01, 0.1 and 1 mg mL<sup>-1</sup>) in the medium. The expression of aromatase  in cultures of primary cells did not change significantly. Significant expression of aromatase  was observed in fat explants at prolactin concentrations of 1 mg mL<sup>-1</sup>. Least squares means ± SE (<i>n</i> = 3). Bars with different letters differ at <i>P</i> &lt; .05. *, ** means differing at <i>P</i> &lt; .05 and <i>P</i> &lt; .01, respectively, between treatments with mammary primary cells and fat explants.</table>

International Journal of Endocrinology

fig2

Figure 2

Figure 2: Mammary Fat Can Adjust Prolactin Effect on Mammary Epithelial Cells via Leptin and Estrogen 