Pulmonary Complications Secondary to Immune Checkpoint Inhibitors

Table 1

Grades of CTCAE version 4.0.

CTCAE grade	Clinical presentation
1	Asymptomatic pneumonitis; clinical or diagnostic observations only
2	Symptomatic pneumonitis; medical intervention indicated; limited instrumental ADL
3	Severe symptoms secondary to pneumonitis; limited self-care ADL; oxygen treatment indicated
4	Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy and intubation)
5	Death secondary to pneumonitis

Abbreviations: ADL: activities of daily living; CTCAE: Common Terminology of Criteria for Adverse Events. Modified from National Cancer Institute ¹².