Erythrocytes and Erythropoietin
1Department of Physiology, University of Tübingen, Gmelin straße 5, 72076 Tübingen, Germany
2Institute for Molecular Cell Biology, University of Saarland, Universitätsklinken Geb. 61, Homburg, 66424 Saar, Germany
3Section of Cell Aging and Degeneration, Department of Therapeutic Research and Medicines Evaluation, Superior Health Institute, Viale Regina Elena 299, 00161 Rome, Italy
4Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Winterthurer straße 260, 8057 Zürich, Switzerland
Erythrocytes and Erythropoietin
Description
Erythrocytes, cells without organelles, are among the most abundant human cells. They participate in the pathophysiology of many disorders as enhanced cell death or lysis of red blood cells may lead to anemia, they are the host cell of the malaria pathogen, and they contribute to the regulation of the microcirculation by S-nitrosohemoglobin. The formation of erythrocytes depends on erythropoietin which itself is regulated by hypoxia-inducible factors, a class of oxygen-sensing proteins.
We invite authors to submit original research and review articles that focus on the cellular physiology of erythrocytes and of erythrocyte-associated disorders. Moreover, we are interested in articles on the action of erythropoietin and hypoxia-inducible factors on a cellular level. Potential topics include, but are not limited to:
- Basic cell biology of erythrocytes
- Cell death, development, and senescence of erythrocytes
- Features and significance of erythrocyte ion channels and erythrocyte membrane transport
- Erythrocyte-dependent regulation of the microcirculation and interaction with endothelial cells
- Role of S-nitrosohemoglobin and erythrocyte-dependent release of NO
- Cellular physiology, pathophysiology, and downstream signaling of erythropoietin
- Cellular physiology and pathophysiology of hypoxia-inducible factors
- Erythropoietin and hypoxia-inducible factors in therapeutic use or as a therapeutic target
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijcb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: