Intermittent Compressive Stress Enhanced Insulin-Like Growth Factor-1 Expression in Human Periodontal Ligament Cells

<div>Intermittent mechanical stress required the intermediate protein to induce<i> IGF-1</i> expression. (a) Cycloheximide (CHX; 10 <i>μ</i>M), (b) genistein (92.5 <i>μ</i>M), and (c) monensin (100 <i>μ</i>M) were pretreated 30 min prior to applying the intermittent mechanical stress for 24 h.<i> IGF-1</i> mRNA expression was determined by real-time PCR. Asterisks indicated statistically significant difference. C: the control condition; S: the intermittent mechanical stress treatment condition.</div>

International Journal of Cell Biology

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Figure 2: Intermittent Compressive Stress Enhanced Insulin-Like Growth Factor-1 Expression in Human Periodontal Ligament Cells 