Review Article
Small-Molecule Theranostic Probes: A Promising Future in Neurodegenerative Diseases
Table 1
Ideal properties for a diagnostic small molecule.
| (i) Stable in vivo | | (ii) Moderately lipophilic | | (iii) Entering the brain in sufficient amounts and retained in the brain | | (iv) Low uptake of metabolites to brain | | (v) Detection of plaques (imaging properties) | | (vi) High specificity for amyloid deposits, low nonspecific bonding | |
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