Small-Molecule Theranostic Probes: A Promising Future in Neurodegenerative Diseases
Figure 3
(a) A 50-year-old man with definite sCJD. Axial DWI shows pathologic hyperintensity in bilateral posterior temporoparietal neocortex. Cortex along parietal-occipital fissure is abnormally hyperintense (vertical arrows), but primary visual region is spared (horizontal arrows). Note asymmetric abnormal hyperintensity in right cingulum (arrowhead). Striatum is uninvolved. (b) FLAIR image at same level shows more subtle pathologic hyperintensity in all abnormal regions on DWI, as shown in cingulate cortex (arrowhead) [10]. (c) Definite sCJD (MM1); total duration: 10 months; EEG at 6 weeks: typical (used to classify case as probable); source: http://www.eurocjd.ed.ac.uk.
