International Journal of Cell Biology

Review Article

Electromagnetic Fields, Oxidative Stress, and Neurodegeneration

Table 2

EMFs effects on oxidative stress and neurodegeneration: in vitro and in vivo experimental models.
Pathology EMFs exposure detailsEMFs effectExperimental modelReference
 RF: 918 MHz, SAR
0.25 WKg−1  
7–9 months		Cognitive benefits
No brain oxidative stress		Tg(AβPPsw ) and non-Tg miceArendash et al. [82]
AD
RF: 918 MHz,
SAR 0.25 and 1.05 WKg−1  
1 hour/day for 1 month		Cognitive benefits
Decreased mitochondria oxidative stress in Tg mice		Tg(AβPPsw + PS1) and non-Tg miceDragicevic et al. [85]
 RF: 918 MHz,
SAR 0.25 and 1.05 WKg−1  
2 hour/day for 2 months		Cognitive benefits
Decreased brain Aβ deposition,
No brain oxidative stress		Aged Tg(AβPPsw + PS1) and non-Tg miceArendash et al. [84]
PDRF: 900 MHz, SAR 0.25 WKg−1  
24 hours		Down-regulation of α-synuclein
No oxidative stress		Neuron-enriched mixed cortical cell culture
from brains of rat embryos (Wistar rats)		Terro et al. [87]
ALSELF: 50 Hz, at 100 and 1000 T
2 hours/day, 5 days/week for 7 weeks		No effectTg (SOD1G93A) and non-Tg micePoulletier De Gannes et al. [88]
 ELF: 60 Hz, 0.7 mT,
2 hours in the morning +
2 hours in the afternoon,
for 8 days		Neuroprotective
Decreased oxidative stress		3NP-treated Wistar ratsTúnez et al. [89]
HDELF: 60 Hz, 0.7 mT,
2 hours in the morning +
2 hours in the afternoon, for 8 days		Neuroprotective
Decreased GSH, GSH-Px,
CAT levels		3NP-treated Wistar ratsTúnez et al. [90]
 ELF: 60 Hz, 0.7 mT,
21 days		Neuroprotective
Decreased oxidative stress		3NP-treated Wistar ratsTasset et al. [91]