The Response of Creatine Kinase Specific Activity in Rat Pituitary to Estrogenic Compounds and Vitamin D Less-Calcemic Analogs

Figure 7

Dose-dependent stimulation of creatine kinase (CK) specific activity by E₂ in pituitary from immature female rats either intact (solid line) or STZ-injected animals (dotted line). Rats were treated and assayed for CK activity as described in Section 2. Results are means ± SEM for 𝑛=5 rats/group. Experimental means compared to control means: ^∗𝑃<.05 and ^∗∗𝑃<.01. Basal activity in Pi from immature intact rat was 0.86+0.04, and from STZ rats was 0.78+0.12𝜇mol/min/mg protein.