Comparison of Antimicrobial Activity against Porphyromonas gingivalis between Advanced Platelet-Rich Fibrin and Injectable Platelet-Rich Fibrin
Table 4
Time-kill kinetics assay: the percent reduction in the number of bacterial colonies compared to the control under the influence of different blood-derived products (A-PRF+ and I-PRF) from the three groups at 3, 6, 12, 24, 36, and 48 h.
Groups
Healthy gingiva
Gingivitis
Periodontitis
values
3 h
A-PRF+
0.05 ± 0.19
0.26 ± 0.19
0.60 ± 0.17
<0.001
I-PRF
0.10 ± 0.23
0.39 ± 0.34
0.71 ± 0.12
<0.001
value
0.412
0.171
0.021
6 h
A-PRF+
0.25 ± 0.18
0.51 ± 0.23
0.71 ± 0.10
<0.001
I-PRF
0.34 ± 0.14
0.67 ± 0.13
0.77 ± 0.07
<0.001
value
0.071
0.008
0.039
12 h
A-PRF+
0.62 ± 0.23
0.73 ± 0.14
0.92 ± 0.05
<0.001
I-PRF
0.73 ± 0.25
0.84 ± 0.05
0.95 ± 0.02
<0.001
value
0.140
0.002
0.032
24 h
A-PRF+
0.37 ± 0.25
0.61 ± 0.08
0.75 ± 0.08
<0.001
I-PRF
0.51 ± 0.32
0.70 ± 0.08
0.81 ± 0.04
<0.001
value
0.117
0.001
0.011
36 h
A-PRF+
0.14 ± 0.30
0.36 ± 0.10
0.36 ± 0.18
<0.001
I-PRF
0.14 ± 0.32
0.46 ± 0.11
0.49 ± 0.14
<0.001
value
0.997
0.004
0.018
48 h
A-PRF+
0.05 ± 0.20
0.08 ± 0.19
0.07 ± 0.21
0.888
I-PRF
0.08 ± 0.18
0.15 ± 0.19
0.28 ± 0.40
0.089
value
0.546
0.220
0.045
Data are presented as the mean ± SD (SD, standard deviation). Comparison between A-PRF+ and I-PRF, two-samplet test; comparison among three patient groups, one-way ANOVA. Statistical significance was set at .
