Research Article

Histopathological and Biochemical Comparative Study of Copper Oxide Nanoparticles and Copper Sulphate Toxicity in Male Albino Mice Reproductive System

Table 2

The percentage of immunoreactivity of Ki67 and CD68 proteins in male mice testes induced by treatment with copper nanoparticles and copper sulphate.

Parameter groupsKi67 immunoreaction (mean ± SD)CD68 immunoreaction (mean ± SD)

Control45.00 ± 7.64a10.00 ± 2.89a
25 mg/kg CuSO411.67 ± 1.67b31.67 ± 1.67b
25 mg/kg CuO NPs31.67 ± 1.67c13.33 ± 1.67c
35 mg/kg CuSO48.33 ± 1.67d36.67 ± 4.41d
35 mg/kg CuO NPs35.00 ± 2.87e15.00 ± 5.00e

Data represent the mean ± standard deviation (SD). Different letters represent a significant difference at .