Histopathological and Biochemical Comparative Study of Copper Oxide Nanoparticles and Copper Sulphate Toxicity in Male Albino Mice Reproductive System

Table 1

Changes in male mice body weight and reproductive organs induced by treatment with copper nanoparticles and copper sulphate.

Treatment groups	Body weight before treatment (gm)	Body weight after treatment (gm)	Testes index (%)	Epididymis index (head) (%)	Epididymis index (tail) (%)	Seminal vesicle index (%)
Control	26.25 ± 1.85	30.82 ± 1.88	0.33 ± 0.13	0.078 ± 0.010	0.069 ± 0.019	0.58 ± 0.18
25 CuSO4	26.33 ± 1.75	22.16 ± 2.48 a	0.29 ± 0.07 a	0.059 ± 0.014 a	0.056 ± 0.017 a	0.34 ± 0.10 a
25 CuO NPs	26.33 ± 1.36	21.15 ± 2.29 a	0.36 ± 0.06	0.061 ± 0.010 a	0.060 ± 0.009	0.64 ± 0.08 a
35 CuSO4	26.16 ± 1.83	22.78 ± 2.10 a	0.30 ± 0.06	0.069 ± 0.018 a	0.07 ± 0.015	0.20 ± 0.08 a
35 CuO NPs	28.86 ± 0.43	24.28 ± 2.31 a	0.27 ± 0.13 a	0.057 ± 0.006 a	0.054 ± 0.007 a	0.51 ± 0.05

Data represent the mean ± standard deviation (SD). A: significant difference at compared with the control.