Effectiveness of Combination of Chitosan Gel and Hydroxyapatite from Crabs Shells (Portunus pelagicus) Waste as Bonegraft on Periodontal Network Regeneration through IL-1 and BMP-2 Analysis

Figure 4

Expression of IL-1 with 1000 times magnification (a) expression IL-1 on the 7th day in the treatment group (a combination of chitosan gel and hydroxyapatite of crab shells), (b) expression of IL-1 on the 14th day in the treatment group (combination of chitosan gel and hydroxyapatite of crab shells), (c) expression of IL-1 day 21st in the treatment group (combination of chitosan gel and hydroxyapatite of crab shells), (d) expression of IL-1 on day 7th in the control group positive (BATAN Hydroxyapatite), (e) 14th-day IL-1 expression in the positive control group (BATAN Hydroxyapatite), (f) 21st-day IL-1 expression in the positive control group (BATAN Hydroxyapatite), (g) IL-1 expression 7th days in the negative control group (placebo gel), (h) IL-1 expression on 14th days negative control group (placebo gel), and (i) IL-1 expression on 21st days negative control group (placebo gel).

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