Determination of the Chemical Composition and Antimicrobial Activity of Lavatera thuringiaca L. Medicinal Herb Material Extracted under Subcritical Conditions by the Liquid Carbon Dioxide Method

Table 3

The results of the chromatographic analysis of the Lavatera thuringiaca L. subcritical CO₂ extract.

No.	RT (min)	Name of compound	The class	Activity	PubChem CID	(%)
1	10.2	Isopulegone	Monoterpenoid	Anticonvulsant, anti-inflammatory, antioxidant, gastroprotective, antistress [19–21]	34645	0.7
2	10.2	D-Menthol	Terpene	Anti-irritant, pain-reliever [22–24]	165675	0.8
3	10.5	Alloaromadendrene	Sesquiterpene	Antioxidant [25]	42608158	0.4
4	10.9	Pulegone	Monoterpenе	Antinociceptive [26]	442495	5.08
5	11.2	Cis-β-farnesene	Sesquiterpene	Antifungal [27]	5317319	7.63
6	11.2	Humulene	Terpene	Anti-inflammatory, appetite suppressant, pain reliever [28, 29]	5281520	0.19
7	14.0	Verbenone	Monoterpenе	Antimicrobial, antifungal, anticonvulsive [30–32]	29025	1.93
8	14.7	Caryophyllene oxide	Terpene	Anticancer and analgesic, anti-inflammatory [33, 34]	1742210	1.35
9	15.2	E-Nerolidol	Terpene	Antifungal, sedative [35, 36]	5281525	0.80
10	16.1	Spathulenol	Sesquiterpenoid	Antioxidant, anti-inflammatory, antiproliferative, and antimycobacterial [37]	92231	6.97
11	16.2	α-Bisabolol oxide B	Sesquiterpene	Anti-irritant, anti-inflammatory, and antimicrobial [38–41]	6432283	9.65
12	16.9	α-Bisabolol	Terpene	Anti-irritant, anti-inflammatory, antimicrobial, analgesic [38–41]	10586	1.36
13	18.7	Bisabolol oxide A	Sesquiterpene	Anti-irritant, anti-inflammatory, and antimicrobial [38–41]	13092559	8.26
14	17.3	Palmitic acid, ethyl ester	Fatty acid	Anti-inflammatory [42]	12366	2.72
15	20.3	Linolenic acid, ethyl ester	Fatty acid	Promitogeinc and activating effects on hepatic stellate cells (HSC), anticancer [43, 44]	5367460	3.15
16	20.4	Phytol	Terpene	Anti-inflammatory, analgesic [45, 46]	5280435	2.49
17	20.9	Myristic acid	Saturated fatty acid	Antimicrobial [47]	11005	2.33
18	23.1	Herniarin or 7-methoxycoumarin	Coumarin	Antigenotoxic, anti-inflammatory, antinociceptive [48–50]	10748	5.61
19	24.6	Stearic acid	Saturated fatty acid	Anticancer [51]	5281	1.14
20	25.0	Elaidic acid	Saturated fatty acid	Against herpesviruses [52]	637517	2.57
21	25.7	Linoleic acid	Polyunsaturated fatty acid	Anti-inflammatory, antibacterial [53–55]	5280450	6.95
22	26.7	Linolenic acid	Fatty acid	Inflammatory, antioxidant, cytotoxic, antibacterial, and antifungal [53, 54, 56]	5280934	9.38
23	36.7	Cannabidiol	Phytocannabinoid	Anticonvulsant [57]	644019	0.96
24	11.5	γ-Muurolene	Sesquiterpene	Antimicrobial, anti-inflammatory [58]	12313020	0.75
25	11.9	Piperitone	Monoterpenoid	Antimicrobial, antiviral, perfume compositions [59]	6987	0.98
26	16.1	Perhydrofarnesyl acetone	Diterpenoids	Perfume composition	10408	1.36
27	10.4	Isocaryophyllene	Sesquiterpene	Antifungal	5281522	0.36
28	11.0	Isovaleric acid	Fatty acid	Sedative, used in the production of validol, valocordin	10430	0.31
29	12.4	α-Curcumene	Sesquiterpene	Antimicrobial, anti-inflammatory, antifungal	92139	0.35
30	14.1	Geranyl linalоol	Diterpene	Antimicrobial, anti-inflammatory	5365872	0.39
31	16.5	Thymol	Monoterpenе	Antiseptic, antibacterial, and antifungal	6989	0.54