The Effect of Okra (Abelmoschus esculentus (L.) Moench) Seed Extract on Human Cancer Cell Lines Delivered in Its Native Form and Loaded in Polymeric Micelles
Table 7
Percentages of apoptotic cells for different doses of the okra seed extract in each cell line.
Control
25 μg/ml
50 μg/ml
100 μg/ml
250 μg/ml
500 μg/ml
750 μg/ml
1,000 μg/ml
Isoquercitrin 28.9 μg/ml
HeLa
Early apoptotic
1.13 ± 0.28
4.13 ± 0.13
3.92 ± 0.72
4.20 ± 0.18
6.18 ± 0.38
6.41 ± 0.23
6.69 ± 0.63
6.55 ± 0.13
5.51 ± 0.22
Necrosis
0.40 ± 0.11
3.57 ± 0.43
5.23 ± 1.03
4.26 ± 0.23
5.18 ± 0.91
5.89 ± 0.17
7.85 ± 0.62
8.38 ± 0.06
3.87 ± 0.08
HepG2
Early apoptotic
0.38 ± 0.02
3.21 ± 0.09
3.97 ± 0.81
5.19 ± 0.21
5.23 ± 0.45
5.36 ± 0.24
12.59 ± 1.12
10.59 ± 0.21
5.83 ± 0.50
Necrosis
0.32 ± 0.03
1.73 ± 0.11
1.67 ± 0.19
1.72 ± 0.08
2.00 ± 0.12
2.19 ± 0.20
3.47 ± 0.38
8.66 ± 0.58
3.22 ± 0.32
MCF-7
Early apoptotic
1.68 ± 0.25
5.37 ± 0.83
5.60 ± 2.46
12.63 ± 0.12
15.21 ± 1.14
15.62 ± 2.47
21.78 ± 6.08
19.34 ± 2.33
3.11 ± 0.73
Necrosis
1.21 ± 0.05
3.34 ± 0.58
3.29 ± 0.61
4.60 ± 0.73
3.87 ± 1.72
5.52 ± 0.47
7.84 ± 1.77
8.05 ± 2.16
3.94 ± 0.40
Results are shown as mean ± SD (n = 3). compared with controls.
