Research Article

Influence of Vanadium 4+ and 5+ Ions on the Differentiation and Activation of Human Osteoclasts

Figure 2

Quantitative analysis of TRAP expression by osteoclasts and monocytes supplemented with osteoclast differentiation cytokines in the presence of increasing concentrations (0 to 3 μM) of V4+ ions. Mean fluorescence intensity (MFI) indicates the average TRAP expression per cell. The MFI value indicates relative TRAP expression when compared with the control (MFI = 121). No differences were noted between the same concentrations of V4+ and V5+ ions () ().