Germline Mutations in BRCA1 and BRCA2 in Breast Cancer Patients with High Genetic Risk in Turkish Population

Table 3

Characteristics of BRCA positive patients.

Patients	Age	ER	PR	CerbB2	1st degree relative breast cancer	Bilateral breast cancer	Both ovarian and breast cancers	BRCA1 mutation	BRCA 2 mutation	BRCA mutations found
4.	34	negative	negative	negative	-	-	-	positive	-	p.R1203 (c.3607C>T)
8.h.g	38	negative	negative	negative	-	-	-	positive	-	p.S1613G (c.4837A>G)
10.r.i	36	positive	positive	negative	-	-	-	-	positive	c.9413dupT
11.s.ö	40	negative	negative	negative	Positive	-	-	positive	-	p.R1203 (c.3607c>T)
12.n.t	60	negative	negative	negative	Positive	-	positive	-	positive	IVS2 +1G>A (c.67+1G>A)
13.e.e	63	negative	negative	negative	-	-	positive	-	positive	IVS2 +1G>A (c.67+1G>A)
15.n.a	38	negative	negative	negative	-	-	-	-	positive	c.9413dupT
21.h. s	47	negative	negative	negative	-	-	-	positive	-	IVS18 +66G>A
										(c.5152+66g>A)
26.u.d	53	negative	negative	negative	-	-	-	positive	-	p.Q356 (c1067A>G)
27.m.a	54	negative	negative	negative	-	-	-	positive	-	p.S1613G(c.4837A>G
44.e.e	43	negative	negative	negative	Positive	-	-	-	positive	c.771_775deTCAA
49.g.t	51	positive	positive	negative	Positive	-	-	positive	-	IVS7 -34C>T (c.442-34C>T)
59.d.a	50	positive	positive		-	-	positive	positive	-	p.W1815 (c.5444G>A)
61.b.b	54	positive	positive	Negative	-	-	positive	positive	-	p.L1209lfs 10 (c.3624dupA)
63.f.s	41	negative	negative	negative	-	-	positive	positive	-	p.W1815 (c.5444G>A)
64.z.e	27	positive	positive	negative	-	-	-	-	positive	c.7487dupA
68.n.k	31	positive	positive	negative	-	-	-	-	positive	p.S1106R (c.3318C>G)
69.ç.g	32	positive	negative	negative	-	-	-	-	positive	P.W3106X(c.9317G>A)
85.d.t	38	positive	positive	negative	-	positive	-	positive	-	p.L1209lfs 10 (c.3624dupA)