Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment

Figure 4

HPLC fluorescence for PTX alone (blue), ALG nanoparticles (green), and ALG-PTX nanoparticles (red). A Zorbax Extend C18 column ( mm ID 5 µm particle size) was used for nanoparticles isolation with a mobile phase 40% of water, 35% acetonitrile (ACN), and 25% methanol and a flow rate of 1.5 mL min⁻¹. Excitation was 232 nm and emission at 353 nm. LU represents luminescence units emitted.