Factors Associated with the Incidence of Local Recurrences of Breast Cancer in Women Who Underwent Conservative Surgery
Table 3
Crude and adjusted odds ratios for statistically significant variables in women with breast cancer who underwent breast-conserving surgery and who were registered in HSRC during the period from January 1, 2000 to December 31, 2010.
Variables
Categories
Crude OR
Adjusted O
value
OR
LI 95%
LS 95%
value
OR
LI 95%
LS 95%
Age group
Less than 39 years
0.007
17.11
2.19
133.63
0.028
10.93
1.29
92.66
40 to 49
0.032
9.13
1.21
68.81
0.083
6.28
0.78
50.23
50 to 59
0.068
6.67
0.87
50.95
0.118
5.33
0.65
43.49
60 to 69
0.122
5.17
0.65
41.43
0.147
4.89
0.57
41.86
70 years and over
1.00
1.00
Race/ethnicity
White
1.00
1.00
Nonwhite
0.090
1.70
0.92
3.15
0.488
1.29
0.63
2.64
Histological type
Ductal and mixed carcinoma
0.080
5.91
0.81
43.35
0.997
1.50
0.10
4.00
Lobular carcinoma
0.042
9.62
1.09
85.21
0.997
1.30
0.20
3.50
Others
1.00
1.00
First treatment after surgery
None
0.998
0.998
RT
0.747
1.28
0.29
5.60
0.886
0.89
0.18
4.40
CT
0.251
2.35
0.55
10.08
0.789
0.80
0.16
4.05
Hormone
1.00
1.00
Size in cm
≤0.5
1.00
1.00
0.6–1.0
0.765
0.81
0.20
3.33
0.413
0.52
0.11
2.47
1.1–1.5
0.426
0.55
0.13
2.38
0.257
0.41
0.09
1.93
1.6–2.0
0.250
2.11
0.59
7.49
0.866
1.13
0.27
4.67
>2.0
0.192
2.26
0.67
7.66
0.673
1.34
0.34
5.27
Vascular and/or lymphatic invasion
No
1.00
1.00
Yes
0.098
1.70
0.91
3.19
0.606
1.22
0.58
2.57
Surgical margin involvement
Negative
1.00
1.00
Positive
0.000
3.48
1.75
6.94
0.001
3.66
1.65
8.09
Oestrogen receptor
Negative
1.00
1.00
Positive
0.091
0.60
0.33
1.09
0.101
0.56
0.29
1.12
Her-2
Negative
1.00
1.00
Positive
0.018
2.03
1.13
3.67
0.045
1.94
1.02
3.72
The total data analysed were based on 676 women (76.8%), due to missing data in at least one variable. could not be calculated because no women with local recurrences remained in this analysis category. RT: radiotherapy, CT: chemotherapy.
