Factors Associated with the Incidence of Local Recurrences of Breast Cancer in Women Who Underwent Conservative Surgery

Table 2

Relationships between sociodemographic and clinical variables and the incidence of breast cancer recurrence in women who underwent breast-conserving surgery and were registered in HSRC during the period from January 1, 2000 to December 31, 2010.

Variable	Category	Recurrence				value
		No		Yes
		= 820	%	= 60	%
Age group	Less than 39 years	76	9%	13	22%	0.003
	40 to 49 years	230	28%	21	35%
	50 to 59 years	240	29%	16	27%
	60 to 69 years	174	21%	9	15%
	70 years or more	100	12%	1	2%
Race/ethnicity	White	278	34%	14	23%	0.086
	Nonwhite	536	66%	46	77%
Location of primary tumour	Nipple	22	4%	2	5%	0.539
	Upper inner quadrant	61	12%	8	21%
	Lower inner quadrant	56	11%	5	13%
	Upper outer quadrant	324	66%	22	58%
	Lower outer quadrant	28	6%	1	3%
Histological type	Ductal and mixed carcinoma	703	86%	54	90%	0.075
	Lobular carcinoma	40	5%	5	8%
	Others	77	9%	1	2%
Stage	Initial	611	95%	56	93%	0.570
	Late	32	5%	4	7%
First postsurgery treatment	None	42	5%	0	0%	0.028
	RT	388	47%	22	37%
	CT	345	42%	36	60%
	Hormone	45	5%	2	3%
Laterality	Right	408	51%	32	53%	0.678
	Left	399	49%	28	47%
Size in cm	0.5 or less	60	8%	3	5%	0.006
	0.6 to 1.0	149	19%	6	10%
	1.1 to 1.5	181	23%	5	8%
	1.6 to 2.0	152	19%	16	27%
	>2.0	257	32%	29	49%
Vascular and/or lymph invasion	No	678	85%	45	76%	0.095
	Yes	124	15%	14	24%
Surgical margin involvement	Negative	752	93%	48	80%	0.001
	Positive	54	7%	12	20%
Lymph node involvement	0	555	75%	39	70%	0.672
	1–3	126	17%	12	21%
	>3	63	8%	5	9%
Sentinel lymph node detection technique	Dye	433	90%	23	88%	0.913
	Radiopharmaceutical	28	6%	2	8%
	Both	22	5%	1	4%
Oestrogen receptor	Negative	141	20%	17	29%	0.088
	Positive	568	80%	41	71%
Progesterone receptor	Negative	173	25%	18	31%	0.270
	Positive	533	75%	40	69%
Her-2	Negative	517	79%	35	65%	0.016
	Positive	138	21%	19	35%
p53	Negative	345	79%	31	69%	0.129
	Positive	93	21%	14	31%

RT: radiotherapy, CT: chemotherapy.