Scopolamine-Induced Memory Impairment in Mice: Neuroprotective Effects of Carissa edulis (Forssk.) Valh (Apocynaceae) Aqueous Extract

Table 2

Effects of C. edulis on brain MDA, glutathione, catalase, AChE activity, and protein concentration of Scopolamine-treated mice.

	Doses (mg/kg)	MDA (mmol/g)	Glutathione (mmol/g)	Catalase (mmol H2O2/mg)	AChE (mol/min/g)	Protein (g/dl)
Control
Scopo	1	^###	^##	^###	^##
C. edulis	62.8
	157
	314
	628
Donepezil	5

Each value represents the (). The level of MDA increases and the antioxidant enzyme level decreases for the Scopolamine group (^##, ^### vs. control), and the administration of C. edulis aqueous extract decreases the level of MDA by increasing the level of antioxidant enzymes (, , and vs. Scopo). One-way ANOVA followed by the Tukey multiple comparison test. Scopo: Scopolamine.