Amyloid-Beta 1-42 Cross-Reactive Antibody Prevalent in Human Sera May Contribute to Intraneuronal Deposition of A-Beta-P-42

Figure 3

Reaction of serially diluted anti-AβP-42 with AβP-42 , presenilin , β-NGF , and tau protein coated ELISA microwells. These four antigens were chosen as being representative of all the antigens that showed immune reactivity to anti-AβP-42 ranging from highly positive to very highly positive. In proportion to the dilution, a significant decline in the reaction of anti-amyloid-β peptide with all 4 antigens was observed.