Drosophila Models of Tauopathies: What Have We Learned?

Table 2

Readouts of Tau toxicity in Drosophila.

Organ/Tissue/Cells	Phenotypes	Promoters/Drivers
Eye	Roughness	GMR
	Photoreceptor cell viability	Gl
		Sev
Notum	Loss of bristles	Eq
Nervous system	Lethality	Elav
	Shortened lifespan	Appl
	Brain vacuolisation	Repo
	TUNEL positive cells	Gl
	Activated caspase3 positive cells	C472
	Loss of olfactory Learning and memory	C772
Motor neurons	Axonal transport defects	D42
	Locomotor deficits	OK6
	“juvenile” phenotype: loss of wing	Elav
	expansion and cuticle tanning	Burs12
		Appl