Research Article
An UPLC-MS/MS Method for Determination of Osimertinib in Rat Plasma: Application to Investigating the Effect of Ginsenoside Rg3 on the Pharmacokinetics of Osimertinib
Figure 3
Typical MRM chromatograms of osimertinib and nilotinib (IS). (a) Blank plasma matrix sample; (b) blank plasma matrix sample spiked with the analytes (at medium concentrations); (c) real plasma sample obtained from rat after intravenous administration of osimertinib.
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