Establishment and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Tigecycline in Critically Ill Patients

Figure 1

Chemical structures and product ion mass spectra of the [M + H]⁺ ions of (a) tigecycline and (b) [t-butyl-d9]-tigecycline (IS).

(a)

(b)