Cholera Infection Risks and Cholera Vaccine Safety in Pregnancy

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Cholera vaccines</td><td class="align_center">Components of cholera vaccines</td><td class="align_center">Characteristics of cholera vaccines</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Type I (Dukoral ®)</td><td class="align_center">Killed whole-cell and recombinant cholera toxin B vaccine</td><td class="align_center">First internationally licensed oral cholera vaccine</td></tr><tr><td class="align_center" colspan="3"><hr/></td></tr><tr><td class="align_left">Type II (ORC-Vax™/mORC-Vax™, Shanchol™, Euvichol®, OraVacs)</td><td class="align_center">Killed whole-cell only vaccines</td><td class="align_center">Manufactured without the cholera toxin B to reduce cost and complexity of vaccine administration</td></tr><tr><td class="align_center" colspan="3"><hr/></td></tr><tr><td class="align_left">Type III (CVD 103, Peru-15, Cuban 638, VA 1.4)</td><td class="align_center">Live attenuated oral cholera vaccine</td><td class="align_center">Mimics the natural cholera infection by inducing mucosal gut immune response</td></tr><tr><td class="align_center" colspan="3"><hr/></td></tr><tr><td class="align_left">Type IV</td><td class="align_center">Parenteral, killed whole-cell cholera vaccines</td><td class="align_center">Administered for a short period of time due to their side effects in the recipients, limited protection for a short duration, and their inability to limit transmission of cholera</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Types, components, and characteristics of cholera vaccines.</div>

Infectious Diseases in Obstetrics and Gynecology

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Table 4

Table 4: Cholera Infection Risks and Cholera Vaccine Safety in Pregnancy 