Review Article

The Role of Normothermic Perfusion in Liver Transplantation (TRaNsIT Study): A Systematic Review of Preliminary Studies

Table 4

Clinical outcomes following normothermic ex vivo perfusion (NMP) of included studies.

StudyPeak AST, days 1–7, U/L, median (range) (NMP vs Control)INR 1 week, median (range) (NMP vs Control)Bilirubin 1 week, μmol/L, median (range) (NMP vs Control)ALP 1 week, U/L, median (range) (NMP vs Control)

Ravikumar et al. [39]417 (84–4681) vs 902 (218–8786) ()1.05 (0.88–1.40) vs 1.03 (0.90–2.22) ()25 (8–211) vs 30 (9–221) ()245 (81–568) vs 243 (76–743) ()

Selzner et al. [42]619 (55–2858) vs 949 (233–3073) ()1.1 (1–1.56) vs 1.1 (1–1.3) ()25.6 (17.1–131.6) vs 47.53 (6.8–256.5) ()202 (96–452) vs 147 (87–456) ()

Bral et al. [43]1252 (383 to >2600) vs 839 (153 to >2600) ()1.1 (1.1–1.6) vs 1.1 (0.9–1.5) ()79 (17–344) vs 53 (8–340) ()139 (40–626) vs 187 (58–524) ()

Liu et al. [44]NA ()NANA (P  > 0.05)NA

Nasralla et al. [45]488.1 (408.9–582.8) vs 964.9 (794.5–1172.0) ()1.24 (1.15–1.38) vs 1.24 (1.16–1.39) ()38.5 (21.0–73.2) vs 49.1 (26.0–85.5) ()NA

AST: aspartate aminotransferase; ALT: alanine amino transferase; ALP: alkaline phosphatase; NA: not available.