Radiological imaging is now crucial in the diagnostic pathway of patients with gastrointestinal disease. In this field, the application of CT and MR is often complementary, and the clinician must cooperate with the radiologist to optimize the right treatment for each patient. Thanks to their characteristic multipanoramic exploration, CT and MR are the main diagnostic investigations used in this setting to answer the main clinical questions. The macro-areas of common interest detected are the following: gastro-intestinal, pancreatic, liver, and biliary tree tumours; gastrointestinal, pancreatic, and biliary tree inflammatory disease; cirrhosis and benign liver lesions.

CT has many advantages, including: very rapid scan times reducing movement artefacts; contrast-enhanced images with arterial and portal phase and the ability to reformat the images in thinner slices, in order to improving resolution. MR, thanks to the high contrast resolution, multiple parameters, and different types of pre-contrast and post-contrast sequences used, is often the diagnostic method of choice in the characterization of lesions and staging of some gastroenterological diseases. Thanks to increasingly innovative techniques in the field of radiology, it might be possible to identify a risk stratification profile of patients affected by gastrointestinal diseases. Therefore, CT and MR could potentially be a decisional factor to stratify patients into more defined clinical categories for precision medicine and appropriate treatments.

The aim of this Special Issue is to provide a guide for CT and MR staging in the tumour pathology of gastric and rectal cancer, and to describe the state of the art of CT and MR in gastroenterology. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

• Imaging in staging of gastric cancer
• Imaging of gastrointestinal stromal tumours before and after target therapy
• Imaging of gastrointestinal neuroendocrine tumours: radiological, clinical and anatomo-pathological findings
• Imaging in staging of rectal cancer: the role of MR
• Imaging of inflammatory bowel disease: current practice and future directions
• Imaging of pancreatic cancer
• Imaging of inflammatory pancreas disease
• Radiological aspects of imaging of benign liver lesions
• Imaging of cirrhosis: radiological surveillance
• Imaging of rare malignant liver lesions
• Imaging in the diagnosis of acute and chronic inflammatory disease of biliary tree
• Imaging in the diagnosis and treatment of tumour disease of biliary tree