Research Article
Predictors of Long-Time Survivors in Nonmetastatic Colorectal Signet Ring Cell Carcinoma: A Large Population-Based Study
Table 1
Differences of clinicopathological characteristics between non-LTS† and LTS among patients with nonmetastatic colorectal SRCC‡.
| | Non-LTS | LTS | | | ≤2 years | 2-5 years | Total | | |
| | Total | 873 | 568 | 1441 | 609 | | | Age | | | | | 0.04 | | ≤40 | 68 (7.79) | 63 (11.09) | 131 (9.09) | 46 (7.55) | | | 41-55 | 154 (17.64) | 124 (21.83) | 278 (19.29) | 143 (23.48) | | | 56-70 | 253 (28.98) | 179 (31.51) | 432 (29.98) | 197 (32.35) | | | >70 | 398 (45.59) | 202 (35.56) | 600 (41.64) | 223 (36.62) | | | Race | | | | | 0.003 | | Black | 89 (10.19) | 61 (10.74) | 150 (10.41) | 38 (6.24) | | | White | 698 (79.95) | 455 (80.11) | 1153 (80.01) | 526 (86.37) | | | Other | 83 (9.51) | 51 (8.98) | 134 (9.3) | 42 (6.9) | | | Unknown | 3 (0.34) | 1 (0.18) | 4 (0.28) | 3 (0.49) | | | Sex | | | | | 0.148 | | Male | 463 (53.04) | 306 (53.87) | 769 (53.37) | 303 (49.75) | | | Female | 410 (46.96) | 262 (46.13) | 672 (46.63) | 306 (50.25) | | | Marital status | | | | | <0.001 | | Married | 437 (50.06) | 309 (54.4) | 746 (51.77) | 371 (60.92) | | | Unmarried | 395 (45.25) | 234 (41.2) | 629 (43.65) | 218 (35.8) | | | Unknown | 41 (4.7) | 25 (4.4) | 66 (4.58) | 20 (3.28) | | | Tumor grade | | | | | <0.001 | | Well/moderately | 37 (4.24) | 48 (8.45) | 85 (5.9) | 62 (10.18) | | | Poorly/undifferentiated | 743 (85.11) | 465 (81.87) | 1208 (83.83) | 469 (77.01) | | | Unknown | 93 (10.65) | 55 (9.68) | 148 (10.27) | 78 (12.81) | | | Tumor size (cm) | | | | | 0.041 | | ≤ 4 | 210 (24.05) | 199 (35.04) | 409 (28.38) | 208 (34.15) | | | 4.1-6 | 261 (29.9) | 148 (26.06) | 409 (28.38) | 148 (24.3) | | | >6 | 281 (32.19) | 171 (30.11) | 452 (31.37) | 177 (29.06) | | | Unknown | 121 (13.86) | 50 (8.8) | 171 (11.87) | 76 (12.48) | | | Tumor location | | | | | 0.044 | | Right colon | 527 (60.37) | 351 (61.8) | 878 (60.93) | 404 (66.34) | | | Left colon | 120 (13.75) | 90 (15.85) | 210 (14.57) | 90 (14.78) | | | Rectum | 209 (23.94) | 118 (20.77) | 327 (22.69) | 105 (17.24) | | | Unknown | 17 (1.95) | 9 (1.58) | 26 (1.8) | 10 (1.64) | | | Number of lymph node examined | | | | | 0.669 | | < 12 | 263 (30.13) | 133 (23.42) | 396 (27.48) | 164 (26.93) | | | ≥ 12 | 597 (68.38) | 430 (75.7) | 1027 (71.27) | 440 (72.25) | | | Unknown | 13 (1.49) | 5 (0.88) | 18 (1.25) | 5 (0.82) | | | T stage | | | | | <0.001 | | Tis-T1 | 43 (4.93) | 34 (5.99) | 77 (5.34) | 65 (10.67) | | | T2 | 23 (2.63) | 45 (7.92) | 68 (4.72) | 51 (8.37) | | | T3 | 433 (49.6) | 306 (53.87) | 739 (51.28) | 390 (64.04) | | | T4 | 374 (42.84) | 183 (32.22) | 557 (38.65) | 103 (16.91) | | | N stage | | | | | <0.001 | | N0 | 201 (23.02) | 218 (38.38) | 419 (29.08) | 304 (49.92) | | | N1 | 187 (21.42) | 146 (25.7) | 333 (23.11) | 155 (25.45) | | | N2 | 485 (55.56) | 204 (35.92) | 689 (47.81) | 150 (24.63) | | | Primary tumor treatment | | | | | <0.001 | | Surgery | 778 (89.12) | 551 (97.01) | 1329 (92.23) | 589 (96.72) | | | Local tumor excision | 12 (1.37) | 6 (1.06) | 18 (1.25) | 14 (2.3) | | | No | 83 (9.51) | 11 (1.94) | 94 (6.52) | 6 (0.99) | | | Radiation | | | | | 0.006 | | Yes | 166 (19.01) | 96 (16.9) | 262 (18.18) | 80 (13.14) | | | No/unknown | 707 (80.99) | 472 (83.1) | 1179 (81.82) | 529 (86.86) | | | Chemotherapy | | | | | 0.04 | | Yes | 468 (53.61) | 329 (57.92) | 797 (55.31) | 306 (50.25) | | | No/unknown | 405 (46.39) | 239 (42.08) | 644 (44.69) | 303 (49.75) | |
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†LTS: long-time survivor; ‡SRCC: signet ring cell carcinoma.
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