ZNF521 Is Correlated with Tumor Immune Cell Infiltration and Act as a Valuable Prognostic Biomarker in Gastric Cancer

Table 3

The correlation analysis between ZNF521 and relate genes and markers of immune cells in TIMER.

Description	Gene markers	STAD		Description	Gene markers	STAD
		purity				purity
		cor	-value			cor	-value
CD8+ T cells	CD8A	−0.219772	***	Dendritic cells	HLA-DPB1	−0.29309	***
	CD8B	−0.121084	*		HLA-DQB1	−0.28247	***
T cells (general)	CD3D	−0.315001	***		HLA-DRA	−0.276107	***
	CD3E	−0.334622	***		HLA-DPA1	−0.276393	***
	CD2	−0.302668	***		BDCA-1 (CD1C)	−0.284624	***
B cells	CD19	−0.218492	***		BDCA-4 (NRP1)	−0.172732	***
	CD79A	−0.268382	***		CD11c (ITGAX)	−0.224098	***
Monocytes	CD86	−0.285611	***	Th1	T -bet (TBX21)	−0.253967	***
	CD115 (CSF1R)	−0.208257	***		STAT4	−0.245164	***
TAM	CCL2	−0.204723	***		STAT1	−0.104384	0.0419837
	CD68	−0.159045	*		IFN-γ (IFNG)	−0.189716	**
	IL10	−0.25374	***		TNF-α (TNF)	−0.280664	***
M1 macrophage	INOS (NOS2)	−0.094312	0.066282	Th2	GATA3	−0.174418	**
	IRF5	−0.111113	0.0303446		STAT6	0.0106501	0.8360634
	COX2(PTGS2)	−0.125946	0.0140167		STAT5A	−0.131781	0.0101217
M2 macrophage	CD163	−0.190151	***		IL13	−0.001852	0.9712901
	VSIG4	−0.16597	*	Tfh	BCL6	−0.134597	*
	MS4A4A	−0.190671	***		IL21	−0.13569	*
Neutrophils	CD66b (CEACAM8)	0.0206156	0.688722	Th17	STAT3	−0.07143	0.1646457
	CD11b (ITGAM)	−0.16399	*		IL17A	−0.122095	0.0172588
	CCR7	−0.291648	***	Treg	FOXP3	−0.241316	***
Natural killer cells	KIR2DL1	−0.076515	0.1365359		CCR8	−0.167921	*
	KIR2DL3	−0.131514	0.0102763		STAT5B	−0.022563	0.6610653
	KIR2DL4	−0.164984	*		TGFβ (TGFB1)	−0.168879	**
	KIR3DL1	−0.124038	0.0155496	T cell exhaustion	PD-1 (PDCD1)	−0.174787	**
	KIR3DL2	−0.161244	*		CTLA4	−0.197054	**
	KIR3DL3	−0.019629	0.7028965		LAG3	−0.227405	***
	KIR2DS4	−0.121695	0.0176306		TIM-3 (HAVCR2)	−0.244911	***
					GZMB	−0.253689	***

*, **, and *** indicate that statistical significance was set at P < 0.05.