Research Article
Baseline Serum Estradiol Level Is Associated with Acute Kidney Injury in Patients with Moderately Severe and Severe Acute Pancreatitis
Table 2
Demographic and clinical outcomes of patients classified by with or without AKI.
| | Variable | Overall | No AKI | AKI | value |
| | Patient numbers | | | | | | Age, yr, | | | | 0.054 | | Male, (%) | 74 (60.66) | 54 (60.67) | 20 (60.61) | 0.995 | | Etiology | | | | 0.994 | | Biliary, (%) | 36 (29.51) | 26 (29.21) | 10 (30.3) | | | Hyperlipidemia, (%) | 58 (47.54) | 42 (47.20) | 16 (48.48) | | | Alcoholic, (%) | 16 (13.11) | 12 (13.48) | 4 (12.12) | | | Idiopathic, (%) | 12 (9.84) | 9 (10.11) | 3 (9.10) | | | Clinical parameters at 48 h | | | | | | Creatinine, mg/dL, | | | | <0.001 | | CRP, mg/L, median (IQR) | 50.60 (13.26-98.65) | 35.28 (12.34-58.10) | 139.8 (65.54-154.2) | <0.001 | | PCT, ng/ml, median (IQR) | 1.66 (0.12-6.79) | 0.72 (0.03-2.35) | 10.19 (4.83-26.5) | <0.001 | | WBC, 103/L, | | | | <0.001 | | APACHE II score | | | | <0.001 | | SOFA score | | | | <0.001 | | Complications | | | | | | Septic shock, (%) | 13 (10.66) | 6 (6.74) | 7 (21.21) | 0.021 | | Respiratory failure, (%) | 19 (15.57) | 10 (11.24) | 9 (27.27) | 0.03 | | Clinical outcome | | | | | | 28-day mortality, (%) | 9 (7.38) | 3 (3.17) | 6 (18.18) | 0.005 | | Length of stay, | | | | <0.001 | | Length of ICU stay, | | | | <0.001 |
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Note: MSAP: moderately severe acute pancreatitis; SAP: severe acute pancreatitis; AKI: acute kidney injury; SD: standard deviation; IQR: interquartile rate; CRP: C-reactive protein; PCT: procalcitonin; WBC: white blood cell count; APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: sequential organ failure assessment. indicates statistical significance, . |
