Identifying the Mechanism of Polygoni Cuspidati Rhizoma et Radix in Treating Acute Liver Failure Based on Network Pharmacology and Molecular Docking

Figure 4

Protein-protein interaction (PPI) network based on the candidate target genes of Polygoni Cuspidati Rhizoma et Radix against acute liver failure. (a) PPI network of the candidate target genes. Each node represents the protein product of an associated target gene. The degree values of the proteins are represented by the node sizes. Colors indicate the connection sources. (b) The top 15 core target genes were identified based on the degree values. The protein with the darkest color has the highest degree value, indicating that it plays the most significant role in the regulation of the network.

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