Research Article

International Normalized Ratio-to-Albumin Ratio as a Novel Marker of Upper Gastrointestinal Bleeding Severity

Table 4

Predictive variables of mortality.

VariablesAUC (95% CI)CutoffSensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)

PTAR0.816 (0.780–0.849)>0.35885.71 (69.7–95.2)64.88 (60.4–69.1)15.0 (12.8–17.5)98.4 (96.5–99.3)
GBS0.657 (0.614–0.697)>594.29 (80.8–99.3)29.55 (25.5–33.8)8.8 (8.1–9.7)98.6 (94.9–99.6)
AIMS65 score0.764 (0.725–0.800)>168.57 (50.7–83.1)69.63 (65.3–73.7)14.0 (11.2–17.5)96.8 (94.9–98.0)
Rockall score (pre-endoscopy)0.736 (0.696–0.773)>394.29 (80.8–99.3)43.39 (38.9–47.9)10.7 (9.7–11.9)99.1 (96.5–99.8)
Rockall score (complete)0.741 (0.701–0.778)>682.86 (66.4–93.4)61.78 (57.3–66.1)13.6 (11.5–15.9)98.0 (96.0–99.0)

AUC, area under the curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; PTAR, prothrombin time-international normalized ratio-to-albumin ratio; GBS, Glasgow–Blatchford score; AIM65, albumin, international normalized ratio, mental status, systolic blood pressure, age >65 years.