Research Article

Serum Lactate Dehydrogenase Is a Sensitive Predictor of Systemic Complications of Acute Pancreatitis

Table 2

Comparison of AP severity scores and complications between AP patients with elevated or normal LDH.

Normal LDH ()Elevated LDH ()-value

Severity
 SIRS (%)31 (21.68)46 (49.46)<0.001
 Ranson1.00 (1.00–2.00)2.00 (2.00–3.00)<0.001
 MODS0.00 (0.00–2.00)2.00 (1.00–4.00)<0.001
 BISAP1.00 (0.00–2.00)2.00 (1.00–3.00)<0.001
 APACHE II7.00 (4.00–10.00)10.00 (6.00–13.00)<0.001
 CTSI2.00 (2.00–4.00)4.00 (2.00–6.00)0.009
Complications
 Pleural effusion (%)51 (35.66)51 (54.84)0.004
 Ascitic fluid (%)18 (12.59)32 (34.41)<0.001
 Myocardial infarction (%)0 (0.00)7 (7.53)0.003
 Pancreatic fluid collection (%)27 (20.61) ()26 (31.71) ()0.068
 Pancreatic necrosis (%)11 (8.40) ()15 (18.29) ()0.032
 AKI (%)8 (5.59)19 (20.43)<0.001
 Acute respiratory failure (%)6 (4.20)8 (8.60)0.161
 Acute heart failure (%)7 (4.90)8 (8.60)0.254

Data are presented as n (%) or median (interquartile range). AKI, acute kidney injury; AP, acute pancreatitis; APACHE, acute physiologic assessment and chronic health evaluation; BISAP, bedside index for severity in acute pancreatitis; CTSI, computed tomography severity index; LDH, lactate dehydrogenase; MODS, multiple organ dysfunction syndrome; SIRS, systemic inflammatory response syndrome.