Effect of Neuroligin1 and Neurexin1 on the Colonic Motility in a Mouse Model of Neuronal Intestinal Dysplasia

Figure 1

Genotyping and autopsy of mice: (a) 173 bp nucleotide sequence of Tlx2 gene was knocked out in Tlx2^-/- mice; (b) distended abdomens were often seen in Tlx2^-/- mice; (c) gross anatomy showed no abnormality in the Tlx2^+/- mice. The appendix, cecum, distal ileum, and proximal colon of the Tlx2^-/- mice were dilated compared to the WT and Tlx2^+/- mice.

(a)

(b)

(c)