Research Article

VSNL1 Promotes Gastric Cancer Cell Proliferation and Migration by Regulating P2X3/P2Y2 Receptors and Is a Clinical Indicator of Poor Prognosis in Gastric Cancer Patients

Table 1

Relationship of VILIP-1 expression with pathological parameters of GC.

Clinical parametersVILIP-1
LowHigh

Age (yrs)-3.781<0.01
Gender0.0810.776
 Male187 (60.1%)124 (39.9%)
 Female77 (61.6%)48 (38.4%)
Location1.7090.426
 Proximal29 (52.7%)26 (47.3%)
 Middle102 (62.6%)61 (37.4%)
 Distal133 (61.0%)85 (39.0%)
Size5.6950.017
 <5 cm167 (65.2%)89 (34.8%)
 ≥5 cm97 (53.9%)83 (46.1%)
Lauren classification47<0.01
 Intestinal170 (76.2%)53 (23.8%)
 Diffuse94 (44.1%)119 (55.9%)
Histology classification2.6560.448
 Papillary adenocarcinoma9 (56.2%)7 (43.8%)
 Tubular adenocarcinoma192 (58.9%)134 (41.1%)
 Mucinous adenocarcinoma21 (72.4%)8 (27.6%)
 Signet ring cell carcinoma42 (64.6%)23 (35.4%)
Histologic differentiation3.3360.343
 Well11 (84.6%)2 (15.4%)
 Moderately77 (60.2%)51 (39.8%)
 Poorly175 (59.7%)118 (40.3%)
 Others1 (50%)1 (50%)
Invasion depth25.748<0.01
 T147 (82.5%)10 (17.5%)
 T277 (70.6%)32 (29.4%)
 T3129 (52.9%)115 (47.1%)
 T411 (42.3%)15 (57.7%)
Lymphatic metastasis30.767<0.01
 No128 (83.1%)38 (16.9%)
 Yes136 (30.4%)134 (69.6%)
Regional lymph nodes32.746<0.01
 PN0128 (77.1%)38 (22.9%)
 PN174 (54.4%)62 (45.6%)
 PN245 (45.5%)54 (54.5%)
 PN317 (48.6%)18 (51.4%)
Distant metastasis17.8<0.01
 No242 (64.5%)133 (35.5%)
 Yes22 (36.1%)39 (63.9%)
TNM stages45.868<0.01
 I74 (82.2%)16 (17.8%)
 II75 (72.1%)29 (27.9%)
 III90 (52.0%)83 (48.0%)
 IV25 (36.2%)44 (63.8%)