Research Article
Clinicopathological Features and Prognostic Implication of Gastric Carcinoma with Lymphoid Stroma
Table 4
The estimated rates of various markers in gastric carcinoma with lymphoid stroma.
| | Number of subsets | Fixed effect (95% CI) | Heterogeneity test ( value) | Random effect (95% CI) | Egger’s test ( value) | Meta-regression test ( value) |
| | EBV positivity | | GCLS | 22 | 0.780 [0.754, 0.805] | <0.001 | 0.723 [0.643, 0.791] | 0.029 | <0.001 | | Non-GCLS | 6 | 0.063 [0.052, 0.076] | 0.067 | 0.064 [0.039, 0.103] | 0.970 |
| | Microsatellite instable | | GCLS | 1 | 0.059 [0.008, 0.320] | 1.000 | 0.059 [0.008, 0.320] | — | — |
| | PD-L1 in tumor cells | | GCLS | 1 | 0.677 [0.497, 0.817] | 1.000 | 0.677 [0.497, 0.817] | — | — |
| | PD-L1 in immune cells | | GCLS | 1 | 0.742 [0.563, 0.865] | 1.000 | 0.742 [0.563, 0.865] | — | — |
| | HER2 | | GCLS | 3 | 0.026 [0.005, 0.120] | 0.883 | 0.026 [0.005, 0.120] | 0.089 | <0.001 | | Non-GCLS | 1 | 0.632 [0.403, 0.813] | 1.000 | 0.632 [0.403, 0.813] | — |
| | p53 | | GCLS | 5 | 0.368 [0.253, 0.499] | <0.001 | 0.386 [0.140, 0.707] | 0.854 | 0.554 | | Non-GCLS | 2 | 0.494 [0.388, 0.600] | 0.401 | 0.494 [0.388, 0.600] | — |
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CI, confidence interval; EBV, Epstein-Barr virus.
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