Improved Survival Outcome and Access to Cancer Screening from Hemorrhoid in Patients with Rectal Cancer

Table 3

Univariate analysis of prognostic factors for DFS and OS.

Prognostic factors	Disease-free survival			Overall survival
	3-year rate (%)	HR (95% CI)	value	3-year rate (%)	HR (95% CI)	value
Age	—	1.00 (0.99-1.02)	0.185	—	1.03 (1.01-1.04)	<0.001
TNM stage
III	61.6	2.61 (1.86-3.66)	<0.001	77.5	2.75 (1.85-4.09)	<0.001
I-II	83.2	1		89.8	1
Differentiation degree
Low	58.1	1.98 (1.37-2.88)	<0.001	74.4	2.22 (1.47-3.36)	<0.001
Moderate/high	77.4	1		87.2	1
Lymphovascular invasion
Positive	52.7	2.41 (1.54-3.77)	<0.001	69.6	2.60 (1.61-4.19)	<0.001
Negative	76.1	1		86.1	1
Perineural invasion
Positive	33.8	2.41 (1.54-3.79)	<0.001	74.5	1.84 (1.05-3.24)	0.033
Negative	73.4	1		85.6	1
Preoperative CEA
>5 ng/ml	64.7	1.78 (1.25-2.53)	0.001	76.4	1.94 (1.29-2.91)	<0.001
0-5 ng/ml	78.5	1		90.2	1
Hemorrhoid history
Yes	86.4	0.39 (0.17-0.88)	0.018	95.3	0.33 (0.12-0.92)	0.034
No	72.8	1		83.5	1

The Cox survival analysis has been applied to all clinicopathological variables, and only significant results were shown in this table. CEA: carcinoembryonic antigen; HR: hazard ratio; CI: confidential interval.