Treatment Adherence in Inflammatory Bowel Disease Patients from Argentina: A Multicenter Study

Table 3

Univariate and multivariate analysis of variables associated with inadequate adherence to 5-aminosalicylates.

	Inadequate adherence group ()	Adequate adherence group ()	Univariate analysis		Multivariate analysis
			OR (CI95%)		OR (CI95%)
Gender (% male)	39.91 (99/248)	40.09 (91/227)	0.9 (0.68-1.43)	0.9
Age, median (IQR)	37 (21-72)	37 (22-68)	N/A	0.9
Years since diagnosis, median (IQR)	6 (1-35)	6.5 (1-34)	N/A	0.7
Primary level of education (%)	8.06 (20/248)	7.49 (17/227)	1.08 (0.5-2.12)	0.8
Lives alone (%)	20.56 (51/248)	15.42 (35/227)	1.42 (0.8-2.28)	0.14
Disability certificate (%)	24.19 (60/248)	22.47 (51/227)	1.1 (0.72-1.68)	0.6
Health coverage (% union-funded health insurance)	43.15 (107/248)	47.58 (108/227)	0.83 (0.58-1.21)	0.3
Smoking (%)	13.31 (33/248)	12.33 (28/227)	1.09 (0.63-1.87)	0.7
History of IBD-related surgery (%)	11.69 (29/248)	16.74 (38/227)	0.65 (0.39-1.12)	0.1	0.77 (0.45–1.31)	0.3
History of hospitalization due to IBD (%)	47.98 (119/248)	52.42 (119/227)	0.83 (0.58-1.2)	0.3
>5 consultations in the last year (%)	43.95 (109/248)	45.37 (103/227)	0.94 (0.65-1.35)	0.7
Satisfaction with number of consultations (%)	78.63 (195/248)	88.11 (200/227)	0.49 (0.29-0.82)	0.006	0.61 (0.35-1.06)	0.08
Perception of easy contact (%)	79.84 (194/248)	91.63 (208/227)	0.36 (0.2-0.64)	0.001	0.43 (0.23–0.81)	0.01
Satisfaction with gastroenterologist’s care (%)	92.34 (229/248)	94.71 (215/227)	0.67 (0.32-1.42)	0.3
Communication with gastroenterologist via email or text messages (%)	66.53 (165/248)	77.09 (175/227)	0.59 (0.39-0.89)	0.01	0.79 (0.51 – 1.24)	0.3
Use chronic medication for other indication than IBD (%)	37.9 (94/248)	27.75 (63/227)	1.59 (1.07-2.34)	0.01	1.49 (1.01–2.25)	0.03

IBD: inflammatory bowel disease; IQR: interquartile range; OR: odds ratio; CI: confidence interval. Statistically significant associated variables after the multivariate analysis are shown in bold.