Preeclampsia and the Risk of Pancreatitis: A Nationwide, Population-Based Cohort Study

Table 2

Incidence densities of the pancreatitis hazard ratio in women with and without preeclampsia stratified by age and presence of comorbidity.

Variables	Preeclampsia						Crude HR (95% CI)	Adjusted HR^† (95% CI)
	No			Yes
	Event	PY	Rate^#	Event	PY	Rate^#
All	113	485211	2.33	52	121327	4.29	1.84 (1.32, 2.55)	1.68 (1.19, 2.36)
Stratify age
≤25	19	66230	2.87	3	16945	1.77	0.61 (0.18, 2.08)	0.58 (0.17, 1.99)
26-35	57	311988	1.83	34	77967	4.36	2.39 (1.56, 3.65)	2.22 (1.43, 3.44)
36-45	37	106993	3.46	15	26416	5.68	1.63 (0.90, 2.97)	1.40 (0.74, 2.64)
Comorbidity^‡
No	99	469860	2.11	41	106185	3.86	1.83 (1.27, 2.63)	1.83 (1.27, 2.63)
Yes	14	15351	9.12	11	15143	7.26	0.80 (0.36, 1.75)	0.80 (0.36, 1.76)

Rate^#: incidence rate per 10000 person-years; crude HR: relative hazard ratio; adjusted HR^†: multivariable analysis including age, alcohol-related diseases, biliary stone, diabetes mellitus, hyperlipidemia, hypertension, hepatitis B, and hepatitis C; comorbidity^‡: patients with any one of the comorbidities alcohol-related diseases, biliary stone, diabetes mellitus, hyperlipidemia, hypertension, hepatitis B, and hepatitis C were classified as the comorbidity group. , , .