Review Article

The Role of H. pylori CagA in Regulating Hormones of Functional Dyspepsia Patients

Figure 2

Effects of gastrointestinal hormones level to mental disorders after H. pylori colonization. CagA-positive H. pylori strains could induce fluctuations in the levels of serotonin (5-HT), ghrelin, dopamine, and cortisol, and might be the cause of some dyspepsia symptoms and mental disorders through blood circulation and brain-gut axis.