Brand Name and Generic Proton Pump Inhibitor Prescriptions in the United States: Insights from the National Ambulatory Medical Care Survey (2006–2010)

Table 1

Predictors of brand name proton pump inhibitor choice among patients prescribed a proton pump inhibitor, 2006–2010.

	Total unweighted sample; ( = 9,677)	Weighted encounters with a brand name PPI, millions (%)^†	value	Adjusted incidence rate ratio (95% CI) of brand name PPI
Year
2006	1753	43.1 (76.0)	<0.0001	Ref
2007	2011	46.2 (74.3)		1.0 (0.9-1.0)
2008	1665	31.8 (51.0)		0.7 (0.6-0.7)
2009	2153	33.3 (42.0)		0.6 (0.5-0.6)
2010	2095	21.7 (31.6)		0.4 (0.4-0.5)
Age category, y
18–24 yrs	144	2.2 (46.1)	0.004	Ref
25–44 yrs	1383	26.9 (57.9)		1.2 (0.9–1.5)
45–64 yrs	3766	70.0 (55.4)		1.2 (0.9–1.5)
≥65 yrs	4384	76.9 (50.7)		1.1 (0.9–1.4)
Sex
Female	5857	111.4 (55.1)	0.004	Ref
Male	3820	64.6 (50.9)		0.9 (0.9-1.0)
Race/ethnicity
White	7478	133.3 (51.4)	0.001	Ref
Black	862	17.6 (59.8)		1.1 (1.0–1.2)
Hispanic/Latino	972	12.4 (38.8)		1.1 (1.0–1.2)
Other	365	5.6 (51.4)		1.0 (0.8–1.1)
Median Income
Q1 (<32.8 K)	2091	37.5 (57.0)	0.2
Q2 (32.8–40.6)	2340	42.7 (53.2)
Q3 (>40.6–52.4)	2375	42.9 (52.7)
Q4 (>52.4)	2339	42.6 (51.5)
Region
South	3318	80.0 (60.0)	<0.0001	Ref
Northeast	1916	34.7 (53.8)		0.9 (0.8–1.0)
Midwest	2515	34.6 (45.8)		0.8 (0.7–0.9)
West	1928	26.8 (47.9)		0.8 (0.8-0.9)
Patient insurance type
Private	3920	77.3 (54.3)	0.1
Medicare	4009	71.1 (51.4)
Medicaid	839	13.7 (58.3)
Other	615	9.0 (56.8)
Unknown	294	4.9 (53.2)
Total number of chronic conditions
0	1917	36.6 (56.5)	0.0001	Ref
1-2	4610	86.9 (55.5)		1.0 (1.0-1.1)
≥3	3150	52.6 (48.8)		0.9 (0.9-1.0)
Provider type
Primary care	4426	95.0 (50.9)	0.002	Ref
Medical spec.	3436	59.0 (57.1)		1.1 (1.0–1.2)
Surgical spec.	1815	22.1 (56.0)		1.1 (1.0-1.1)
Practice ownership
HMO	217	0.7 (13.8)	<0.0001	Ref
Physician-owned	7174	148.9 (55.6)		3.6 (2.0–6.4)
Community health center	982	4.0 (52.5)		3.7 (2.0–6.7)
Academic medical center	197	3.9 (58.9)		4.0 (2.2–7.3)
Other	1093	17.8 (43.4)		3.2 (1.8–5.6)
Metropolitan status of practice
MSA	8342	151.3 (53.7)	0.6
Non-MSA	1335	24.7 (52.2)

As a percentage of the total number of patients prescribed a PPI, adjusted for sample weights.